Description

Mitochondrial haplogroup U is one of the oldest mtDNA haplogroups in Europe and the Near East, and contains several historically important subclades. U5 is considered the most ancient surviving European maternal haplogroup — it was carried by the first anatomically modern humans who entered Europe approximately 45,000 years ago and is still found today at elevated frequencies in the Sami (48%) and other Northern Europeans who preserve Mesolithic hunter-gatherer ancestry. U2e is associated with Yamnaya steppe ancestry and is found across Eastern Europe. Subclade K (U8b) is notably common among Ashkenazi Jews (~32%) and among Druze. U6 spread into North Africa.

Interesting Fact

Haplogroup U5 is the oldest surviving European maternal lineage, originally carried by the hunter-gatherers who first colonised Europe after the Out-of-Africa migration and who are still genetically detectable in modern European populations roughly 45,000 years later — a living thread connecting present-day Europeans to the Ice Age.

Distribution by Ethnicity

Ethnic distribution Region Frequency Sample
Sami Northern Europe
48%
Basques Western Europe
22%
Europeans (average) Europe
15%
Near Easterners Near East
12%
South Asians South Asia
12%
Berbers North Africa
10%

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References

  1. Torroni et al. (2006) — Harvesting the fruit of the human mtDNA tree. Trends in Genetics 22(6), 339–345.
  2. Bramanti et al. (2009) — Genetic discontinuity between local hunter-gatherers and central Europe's first farmers. Science 326(5949), 137–140.
  3. Malyarchuk et al. (2010) — The peopling of Europe from the mitochondrial haplogroup U5 perspective. PLOS ONE 5(4), e10285.