Description

Haplogroup L0f is one of the deep branches of L0, the oldest macrohaplogroup in the human mtDNA tree. L0f is found in Tanzania and Mozambique among Khoisan-related populations and various East African groups. It represents one of the most ancient surviving maternal lineages in humanity, diverging from the main L0 trunk hundreds of thousands of years ago. L0f and its sister lineages in L0 provide evidence for the extraordinary depth of genetic diversity in sub-Saharan Africa, particularly in East and Southern Africa.

Interesting Fact

L0 is the oldest surviving human mtDNA macrohaplogroup, and its deep branches like L0f represent some of the most ancient maternal lineages on Earth. The coalescence date of L0 with the rest of the human mtDNA tree coincides with estimates for the emergence of anatomically modern Homo sapiens in Africa, making L0 and its sub-branches direct witnesses to the earliest period of modern human evolution in Africa.

Distribution by Ethnicity

Ethnic distributionRegionFrequencySample
Tanzanian hunter-gatherers (Sandawe)East Africa
12%
n=100
Tanzanian pastoralistsEast Africa
5%
n=150
MozambicansEast Africa
4%
n=100
East Africans (average)East Africa
2%
n=500

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References

  1. Behar et al. (2008) — The dawn of human matrilineal diversity. American Journal of Human Genetics 82(5), 1130–1140.
  2. Gonder et al. (2007) — Whole-mtDNA genome sequence analysis of ancient African lineages. Molecular Biology and Evolution 24(3), 757–768.